Could weight worries be due to something
deeper than caloric intake and use?
About.com's thyroid Guide, Mary, pointed out in her blog today an article that I found interesting: Dr. Kent Holtorf suggests that "leptin resistance" and excessive production of a form of thyroid hormone known as "Reverse T3" could be an underlying cause of weight gain or weight-loss difficulty.
You can read the full article at the Huffington Post this week in his article titled Long Term Weight Loss -- More than Will Power?. In the post, Dr. Holtorf says that "[Weight gain] is not simply a problem that individuals are taking in more calories ... or lack of exercise or willpower.". Rather, he suggests that weight-loss failure can more than likely be attributed to endocrine or metabolic dysfunction.
Could the key to weight loss really be something beyond the old, trusted theory of "calories in/calories out"? Will research definitively show that something else leads to weight gain?
Or... Aside from actual health conditions that can cause weight gain (e.g. Cushing's disease), does it ultimately come down to caloric energy taken in and spent?
